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Louisiana bill would allow opioid settlement funds for psychedelic research

March 26, 2026

Louisiana lawmakers are advancing Senate Bill 43, a proposal that would allow opioid settlement funds to support clinical research into psychedelic-assisted therapies, including ibogaine and psilocybin. The legislation would establish a state-run program within the Louisiana Department of Health to partner with academic institutions and conduct FDA-regulated trials for substance use disorders and treatment-resistant mental health conditions. While the substances would remain illegal for general use, the bill outlines a tightly controlled clinical framework and reflects a broader effort to use unspent opioid settlement funds for innovative treatment approaches.

The proposal is supported by testimony from veterans and clinicians who describe ibogaine and similar therapies as potentially transformative, particularly for individuals who have not responded to conventional treatments. At the same time, the article highlights ongoing scientific and regulatory challenges, including limited large-scale clinical data and known safety risks. If approved, the program would position Louisiana among a growing number of states exploring psychedelic research, with the goal of expanding access through formal clinical trials rather than informal treatment abroad.